Gout is a form of arthritis caused by excess uric acid in the bloodstream. It
manifests as joint pain accompanied by swelling, redness and limited range of
motion. The pain usually comes on suddenly and can cause a sensation of
warmth at the affected area. While there are more than 100 types of
arthritis—each with varying causes, risk factors and symptoms—gout is among
the most common.
Gout typically occurs in the feet and most often at the base of the big toe. Other
less common areas include the knee, hand, wrist and elbow. It’s more likely to
affect men, post-menopausal women, diabetics, people with poor kidney
function and those with other underlying health conditions.
Gout has no cure, but can be managed with medication. Often patients are
prescribed oral medications including NSAIDs, colchicine, allopurinol and
corticosteroids. Some patients experience periods of remission of a year or
longer, in which case oral medications for the occasional flare-up can be
sufficient. However, gout pain can also occur more often, in which case infusion
therapy can help.
Pegloticase (trade name Krystexxa) is an IV medication for the treatment of
severe and chronic gout. It is a treatment for those whose other treatments are
not tolerated or not otherwise working. In clinical trials, Krystexxa was shown to
lower levels of uric acid and reduce deposits of uric acid crystals in joints and soft
tissue. Typically, Krystexxa is administered every two weeks over a six-month
period, and takes about two hours per infusion.
If you are struggling with frequent flare-ups from gout and oral medications are
not controlling your condition, you might be a candidate for Krystexxa. Please
contact your physician to inquire about this infused medication or contact
Heartland Infusion Pharmacy and we’ll guide you through the process of making
a physician request for this treatment.